Louisville vs Virginia Tech Preview and Prediction

Date & Time: Saturday, November 1, 2025 at 3 p.m. ET
Location: Lane Stadium, Blacksburg, Virginia
Matchup: Virginia Tech (3-5 overall, 2-2 in ACC) vs. Louisville (6-1 overall, 3-1 in ACC)
Television: The CW Network

Virginia Tech continues to have a talent gap but the game against Cal showed they can still be competitive. The next step is to use that momentum to score a win over a top 25 team. Louisville is very good but they are beatable. Especially playing in Lane. This is a big opportunity for Philip Montgomery and his guys to score a big win.

The Hokies need to run the same offense they did against Cal. Run the ball as many ways as Philip Montgomery can think of. Tech’s best offensive weapons are Kyron Drones, Marcellous Hawkins and Terion Stewart running the ball. Those three options give opponents more to think about than trying to force a passing game which hasn’t worked well this season. And as we saw last week, when the run game is working it opens up opportunities in the passing game.

Louisville has an explosive offense. This will be a much tougher task than Cal last week. Hopefully the defense is starting to figure it out and will be able to get some stops. Players to watch are RB Isaac Brown and WR Chris Bell. Both of those guys are game breakers and can make big plays when they get the ball in their hands.

In order to have a shot this week, the Hokies need to win the turnover battle. Capitalizing on a short field or two would help to even up this game a bit. If the turnover battle is even, that favors Louisville which should have a significant advantage when they have the ball.

Louisville looks every bit the part of a top 25 team. They beat #2 Miami two weeks ago. This is a team that scores a lot of points. They have many different ways they can beat you. The Hokies best chance is to control the clock, limit possessions and force a turnover or two. Otherwise, on paper, it looks like Louisville has a pretty significant advantage in this game.

Prediction: Louisville 34, Virginia Tech 20

📈 Betting Line & Market

  • Odds: Louisville favored by about 10.5 points, with total expected points ~ 53.5.

Market snapshot

  • Spread/Total/Moneyline: Louisville -10.5 (≈ -420), O/U 53.5, VT +325.
  • Implied score from market: ~Louisville 32 – VT 22 (solve from spread + total)
  • Implied win probs from ML: Louisville ~80.4%, VT ~23.6%. (Derived from -420/+325 posted by FOX Sports)

Public/computer angles

  • FOX/Data Skrive model: Louisville 37–19 (Louisville -10.5, Over).
  • SP+ (Bill Connelly via SI): Projects Louisville 35–19, Cardinals by 15.3 with VT win prob 17%; O/U projection 53.5. This is ~5 points stronger on Louisville than the market.
  • OddsShark computer: Predicted 34.4–24.6 (leans Louisville -10.5; predicted sum is ~59).
  • Consensus line checkers/news: Most outlets list Louisville -10.5 / 53.5; BetMGM listed -10.5 on Tuesday.

Spread:

  • Market: LOU -10.5.
  • SP+ fair line: LOU -15.3 → ~4.8 points of value toward Louisville vs. current spread.
  • Other computers (FOX/OddsShark) sit around LOU by 12–18

Total:

  • Market: 53.5.
  • SP+: 53.5 (no edge). FOX model sum 56 (slight Over).

Moneyline:

Market implies ~80% Louisville. SP+ VT win prob ~17% → aligns with the favorite being heavy.

2025 Preseason ACC Predictions

A preseason prediction for all 17 ACC teams heading into the 2025 college football season.

Projected ACC StandingsComments

12-0
Clemson looks like a complete team that could be 13-0 headed into the CFP

11-1
Expect Kevin Jennings to take a bit of a step back this year but the schedule almost assures a really strong season.

10-2
Color me a bit skeptical of Mario Cristobal and Miami but the schedule is there to be a CFP contender.

9-3
The Haynes and Haynes combo is not to be trifled with. Brent Key seems to have finally found a roster that can compete for an ACCCG berth.

9-3
Manny Diaz proved me wrong last year. With a good transfer QB and soft schedule, they will make noise this year.

8-4
Offense should be really good. Defense — who knows?

8-4
Dave Doeren is usually able to pull together a solid squad every year but will that defense hold up after all the transfers?

6-6
Too much talent to be as bad as last year. Will the new influx transfers this year work out for them? Hard to pick anything but middle of the road.

6-6
Solid additions through the portal but Brent Pry is still the head coach.

6-6
Pitt and Pat Narduzzi are trending toward becoming a perennial 6-6 team.

5-7
Bill Belichick is a football genius but he doesn’t block, tackle or run the ball.

5-7
They have a great RB and that’s pretty much it. However, that may be enough to win 5 games with that schedule.

4-8
Tough schedule and not enough talent. Not a great combination.

4-8
Fran Brown might get a reality check in year 2.

4-8
Soft schedule might help them out a lot but ultimately they have to show they have become a better team when they hit the field.

3-9
Cal football looks lost at the moment. At least they have the #Calgorithm.

3-9
Tough schedule. Transfer losses. Interim head coach and a new AD trying to make his mark. Looks like a bottom-out season for Stanford.

2024 ACC Football Preseason Predictions

This week we are doing ACC preseason predictions from our favorite Hokie podcast and Twitter personalities. We have preseason picks from Twitter personality OXVT (@OX_VT), Brian Seigla (@seigs5052) from the Boundary Corner Podcast, and Pete B. (@petebvt) from the Two Deep Podcast. We are also joined by ACC contributors Casey (Clemson) and Dirty Bird (Miami) with their picks for the 2024 ACC football season.

Treadmillhorse (@treadmillhorse)OX_VT
(@OX_VT)
Brian Seigla
(@seig5052)

11-1

11-1

11-1

10-2

10-2

10-2

10-2

9-3

9-3

9-3

8-4

9-3

9-3

9-3

8-4

9-3

8-4

8-4

8-4

8-4

8-4

8-4

8-4

7-5

6-6

8-4

7-5

5-7

7-5

6-6

5-7

6-6

6-6

5-7

6-6

6-6

5-7

4-8

5-7

4-8

5-7

5-7

4-8

5-7

5-7

3-9

4-8

3-9

3-9

3-9

3-9
ACC OPOYCam Ward, MiamiPreston Stone, SMUKyron Drones, Virginia Tech
ACC DPOYBarrett Carter, ClemsonAshton Gillotte, LouisvilleBarrett Carter, Clemson
ACC CoachDave Doeren, NC StateRhett Lashlee, SMUBrent Pry, Virginia Tech
Champ GameClemson / Florida StateClemson / SMUClemson / Florida State
ChampionClemsonClemsonFlorida State
Pete B.
(@petebvt)
Casey
(@FromSluggo)
DIRTY BIRD
(@dirtyyybird)

10-2

11-1

11-1

9-3

10-2

10-2

9-3

10-2

8-4

9-3

9-3

8-4

9-3

9-3

8-4

9-3

9-3

8-4

7-5

8-4

7-5

7-5

8-4

7-5

7-5

7-5

7-5

6-6

7-5

6-6

6-6

6-6

6-6

6-6

6-6

5-7

5-7

5-7

4-8

4-8

3-9

4-8

4-8

3-9

4-8

4-8

3-9

3-9

4-8

2-10

3-9
ACC OPOYKyron Drones, Virginia TechPhil Mafah, ClemsonCam Ward, Miami
ACC DPOYFrancisco Mauigoa, MiamiAshton Gillotte, LouisvilleRueben Bain, Miami
ACC CoachBrent Pry, Virginia TechBrent Pry, Virginia TechBrent Pry, Virginia Tech
Champ GameFlorida State / Virginia TechClemson / Florida StateMiami / Virginia Tech
ChampionFlorida StateClemsonMiami

Louisville vs Virginia Tech Preview and Prediction

This is the best that Virginia Tech football has looked in a couple of years. The offense, defense and special teams all appear to be getting the job done right now. The last three wins have not come against great competition but it has been an opportunity for the Hokies to build some confidence. They looked like a very confident team on Thursday against Syracuse.

SP+ Rankings

Virginia Tech

Overall: 59th
Offense: 80th
Defense: 37th
Special Teams: 22nd

Louisville

Overall: 24th
Offense: 32nd
Defense: 19th
Special Teams: 41st


Louisville’s offense is predicated on the run. They lean on star RB Jawhar Jordan to do the heavy lifting. The one game where he went out early is the only game they have lost this season. Virginia Tech should focus on bottling up Jordan and make QB Jack Plummer beat them with his arm. This should be a good test for the Virginia Tech defense that has had trouble stopping the run against talented running backs this season.

Louisville is top-10 in the nation at stopping the run. If the Hokies hope to move the ball against this defense, it will have to be through the air. This is a game where Tech will need Jaylin Lane and Da’Quan Felton to show up huge in the passing game. Louisville is not going to let Tech’s running game have a day like they did against Syracuse.

Louisville is an extremely well-coached team. This team has done an exceptional job of handling their business this year. They have talent, they are well-coached and have a good gameplan each week. On paper, Louisville should be the clear #2 team in the ACC right now behind Florida State. Virginia Tech has a chance in this game. They need to come in an play their best game of the season. They need a clean game defensively where they do not give up big runs to Jawhar Jordan. And they need to be turnover-free on offense. Based on how Tech has been playing recently, I think they can keep this a competitive game but Louisville is clearly one step ahead of where the Hokies are right now.

Prediction: Louisville 33, Virginia Tech 23

2023 ACC Football Preseason Predictions

This week we are doing ACC preseason predictions from our favorite Hokie podcast and Twitter personalities. We are joined by @OX_VT, @PeteBVT from the Two Deep Podcast, Brian Seigla from the Boundary Corner Podcast, Dan (@Visionary_SZN) from the Tales from the Terrordome Podcast, @DriftVT from the @VT4L Podcast and Hokie Pharmacist from Main Street Pharmacy with their picks for the 2023 ACC football season.

Treadmillhorse (@treadmillhorse)
12-0
10-2
10-2
8-4
8-4
8-4
7-5
7-5
6-6
6-6
5-7
5-7
3-9
2-10
ACC Offensive Player of the YearDrake Maye
ACC Defensive Player of the YearJeremiah Trotter Jr.
ACC Coach of the YearPat Narduzzi
ACC Title Winner
OX_VT (@OX_VT)
10-2
9-3
9-3
9-3
8-4
8-4
8-4
7-5
6-6
6-6
5-7
4-8
4-8
2-10
ACC Offensive Player of the YearBrennan Armstrong
ACC Defensive Player of the YearJeremiah Trotter Jr.
ACC Coach of the YearBrent Pry
ACC Title Winner
Pete B. (@PeteBVT)
from the Two Deep Podcast
11-1
11-1
8-4
8-4
8-4
7-5
7-5
7-5
7-5
6-6
6-6
5-7
4-8
2-10
ACC Offensive Player of the YearWill Shipley
ACC Defensive Player of the YearJared Verse
ACC Coach of the YearMike Norvell
ACC Title Winner
Brian Seigla (@Seig5052)
from the Boundary Corner Podcast
12-0
10-2
9-3
9-3
8-4
8-4
7-5
7-5
7-5
6-6
5-7
4-8
4-8
2-10

ACC Offensive Player of the YearDrake Maye
ACC Defensive Player of the YearJared Verse
ACC Coach of the YearMike Norvell
ACC Title Winner
Dan (@Visionary_SZN)
from the Tales from the TerrorDome Podcast
10-2
9-3
9-3
8-4
8-4
7-5
7-5
7-5
6-6
6-6
5-7
4-8
3-9
2-10

ACC Offensive Player of the YearBrennan Armstrong
ACC Defensive Player of the YearJared Verse
ACC Coach of the YearMike Norvell
ACC Title Winner
@DriftVT
from the @VT4L Podcast
11-1
9-3
9-3
8-4
7-5
7-5
7-5
6-6
6-6
6-6
6-6
4-8
3-9
2-10

ACC Offensive Player of the YearJordan Travis
ACC Defensive Player of the YearJeremiah Trotter Jr.
ACC Coach of the YearMario Cristobal
ACC Title Winner
Hokie Pharmacist (@HokiePharmacist) *
12-0*
12-0
10-2
9-3
9-3
9-3
8-4
8-4
7-5
5-7
5-7
4-8
4-8
0-12

ACC Offensive Player of the YearGrant Wells*
ACC Defensive Player of the YearDrake Maye*
ACC Coach of the YearDave Clawson
ACC Title Winner

* See the full Hokie Pharmacist Twitter thread here:

Louisville Preview and Prediction

One of the biggest issues of the Fuente era is losing games this team shouldn’t lose. And it’s not that Wake Forest is a bad team — they’re not. It’s that they are still a team that a talented group like Virginia Tech should be able to beat most of the time. In order for this program to take the next step, those are the types of games that need to be wins far more often than not.

SP+ Rankings

My prime example of the ACC having a dysfunctional scheduling model is Louisville. They joined the league in 2014 and their first game with the Hokies is in 2020. You wouldn’t think these two programs are in the same league given how few times they’ve played. The ACC needs to change the scheduling model so that member schools are able to play each other more often. Six years between meetings seems like too long.

Louisville can be explosive offensively — but they don’t do it consistently. This is a team that scored 48 on Florida State and 7 against Notre Dame. Their week-to-week offensive outputs raise some questions. They have talent on the offensive side of the ball. That’s not their problem. The problem is that they are not always consistent moving the ball on offense. They rely on big plays to score. But when the big plays aren’t there, they struggle to move the ball down the field.

Louisville’s defense is just as inconsistent as their offense. They gave up 47 points to Miami (and 46 to Georgia Tech) and also gave up 12 to Notre Dame. It’s kinda hard to believe. The one consistent aspect of their defense is that they give up yards on the ground. The Hokies should be able to move the ball on the ground against this defense. Louisville is stronger against the pass. If the Cardinals sell out against the run, Hendon Hooker will need to prove that he can beat them with this arm.

Both teams have consistency issues. I’m a big believer in the bounce-back game in college football. The Hokies had a bad loss last week and we will see a more inspired effort this week. This team has too much talent on the offensive side of the ball to think we’ll see a repeat performance of last week. What will be key is stopping Louisville’s big plays when Virginia Tech is playing defense. You don’t want to get into a shootout on the road with Louisville. Put me down as thinking the Hokies bounce back and win a squeaker on the road.

Prediction: Virginia Tech 33, Louisville 30

ACC Predictions

These predictions are also featured on allsportsdiscussion.com here, here and here.

Coastal Predictions

Georgia Tech 8-4 (6-2)
Duke 9-3 (6-2)
Virginia Tech 8-4 (5-3)
Miami 6-6 (4-4)
Pittsburgh 6-6 (4-4)
North Carolina 6-6 (3-5)
Virginia 2-10 (1-7)

Everyone is saying that the division will come down to the Virginia Tech-Georgia Tech game on November 12th. I tend to agree but I could see Virginia Tech winning that game with 12 days to prepare but lose three games in the rest of ACC play to still hand the division to Georgia Tech. Virginia Tech definitely has the easier ACC slate only having to face Boston College and NC State from the Atlantic division. Georgia Tech, on the other hand, has to face Clemson and Florida State (yikes!).

I see Duke keeping the momentum going under David Cutcliffe. I think we will continue to see Duke be a thorn in the side of other Coastal teams for years to come. I call them the Stanford of the east. Miami will have another Miami-like season, not bad but not great. Probably not enough to save Al Golden’s job. North Carolina will continue to put up points like usual but I’m not sure I trust that defense to show up. I’m not really sure what to expect from Pitt under new coach Pat Narduzzi. I could see them being really good but more than likely they’ll have an up and down season.

And finally Virginia. I actually feel bad for Virginia. Seems like most have already jumped ship on Mike London’s future there and then they get handed a murderer’s row non-conference schedule (@UCLA, Notre Dame & Boise State). Not good.

Atlantic Predictions

Florida State 11-1 (7-1)
Louisville 10-2 (7-1)
Clemson 10-2 (7-1)
Boston College 7-5 (4-4)
North Carolina State 5-7 (2-6)
Syracuse 3-9 (1-7)
Wake Forest 2-10 (0-8)

Florida State still is one of the most talented teams in the country. They have plenty of talent to choose from and will reload in 2015. They will not, however, go undefeated in 2015. The Atlantic division will be a three team race between Florida State, Clemson and Louisville. Clemson has the best quarterback in the league to go along with an improving defense under Brent Venables.

Louisville’s defense will be good enough to keep them in every game. As long as they can find competent quarterback play, they will be a force to be reckoned with. Boston College will continue to be a tough out for anyone they play but that schedule is brutal. Even with raised expectations, I expect NC State to take a step back. I’m not buying the hype there. Syracuse and Wake Forest are a step below the rest of the division.

Closing Thoughts

Finally, the ACC has more than two good teams! I think the ACC will get some respect this year. Between Florida State, Clemson, Louisville, Georgia Tech, Virginia Tech and Duke, the ACC has six potential top-25 teams. This is the year to expect the unexpected. Both divisions will have razor thin races going into November. You can look as far as the six games between the teams listed above to decide both divisions. I could even see some crazy tiebreakers go into effect in those division races. It’s been awhile since the league had ranked teams battling it out in each division. Should be an exciting season.